Developing a predictive model of human skin colouring
نویسندگان
چکیده
A model of colour formation within human skin has been developed to aid the characterisation of pigmented skin lesions from their digitized colour images. The model is based on the Kublenka–Munk theory of scattering and absorption within inhomogeneous materials and the physics pertaining to their colour properties. By considering the skin to be a layered construction of such materials, the stratum corneum, epidermis, papillary dermis and reticular dermis, and by exploiting the physics related to the optical interface between these layers, the model generates all possible colours occurring within normal human skin. In particular, the model predicts that all skin colours have to lie on a simple curved surface patch within a three-dimensional colour space bounded by two physiologically meaningful axes, one corresponding to the amount of melanin within the epidermis and the other to the amount of blood within the dermis. These predictions were verified by comparing the CIE LMS coordinates of a representative, cross-racial sample of fifty skin images with the LMS coordinates predicted by the model. The results show that, within the predicted error bounds, the coordinates for normal skin colours do indeed lie on the curved surface generated by the model. Several possible applications of this representation are outlined, including images representing the melanin and blood components separately, as well as the possibility of measuring the Breslow thickness of melanocytic invasion within malignant melanoma.
منابع مشابه
Improving Simulation Accuracy of a Downsized Turbocharged SI Engine by Developing a Predictive Combustion Model in 1D Simulation Software
In this paper we aim to develop a predictive combustion model for a turbocharged engine in GT-Power software to better simulate engine characteristics and study its behavior under variety of conditions. Experimental data from combustion was initially being used for modelling combustion in software and these data were used for model calibration and result validation. EF7-TC engine was chosen for...
متن کاملPredictive Control With Filtering Of Input And Output Variables
The paper is focused on an implementation of a predictive controller with a colouring filter C in a disturbance model. The filter is often essential for practical applications of predictive control based on transfer function models. It is commonly considered as a design parameter because it has direct effects on closed loop performance. In this paper a computation of predictions for the case wi...
متن کاملRejection of the Feed-Flow Disturbances in a Multi-Component Distillation Column Using a Multiple Neural Network Model-Predictive Controller
This article deals with the issues associated with developing a new design methodology for the nonlinear model-predictive control (MPC) of a chemical plant. A combination of multiple neural networks is selected and used to model a nonlinear multi-input multi-output (MIMO) process with time delays. An optimization procedure for a neural MPC algorithm based on this model is then developed. T...
متن کاملPredictive Control with Filtered Input and Output Variables in Prediction Equations
The paper is focused on an implementation of a predictive controller with a colouring filter C in a disturbance model. Both single-input-single-output (SISO) and multi-input-multi-output (MIMO) cases were considered and analysed. The filter is often essential for practical applications of predictive control based on input-output models. It is commonly considered as a design parameter because it...
متن کاملDeveloping a CoMSIA model for inhibition of COX-2 by resveratrol derivatives
Design of selective cyclooxygenase-2 (COX-2) inhibitors is still a challenging task because of active site similarities between COX isoenzymes. To help with this issue, we tried to generate a 3D-QSAR (3 dimensional quantitative structure activity relationship) model that might reflect the essential features of COX-2 active sites. Compounds in a series of resveratrol derivatives inhibitors with ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 1996